Friday, July 25, 2014

Bacteria to Cure Obesity

After reviewing several articles I came across an article that talked about using bacteria that occurs naturally in the gut to prevent obesity and type 2 diabetes. I thought this would be a great topic to write about because we just finished the discussion on fecal transplants that provided bacteria from a healthy donor to an unhealthy patient, resulting in stabilization of the unhealthy patients gut bacteria.
Obesity and type 2 diabetes are characterized by symptoms including inflammation changes in the composition of the intestinal bacteria and the disruption of the natural barrier in the intestines. The healthy bacteria was found in large numbers in humans that were not overweight and fewer in humans and rodents with inflammation or obesity. In this study scientist from Vanderbilt University, tested the Akkermansia bacteria, which is a healthy bacteria that occurs naturally in the guts of humans and animals. Akkermansia muciniphila is found in the intestinal mucus layer that protects against intruders. This bacteria was studied in mice. Researchers gave mice a high fatty diet and placed the healthy bacteria in their water. The mice showed a reduction in their weight and maintained a healthy weight compared to the controlled group of mice. The mice where given the bacteria over a course of eight weeks. The mice that were given the bacteria had dramatically lower food intake, body fat, insulin resistance and fatty liver, compared to the controlled group. The presence of this healthy bacteria, strengthen the intestinal barrier and also decreased weight gain and inflammation reactions in fatty tissues and insulin resistance.  The bacteria also increased endocannabinoid levels, which is a substance that ensures blood glucose remains at the correct level. They also found that the mice that were given the bacteria still showed effects of the bacteria 4 weeks after the bacteria had been stopped. There was also a difference in the liver of the mice, which showed that the bacteria were affecting areas beyond the gut.

This was amazing research. I cannot believe that we could be on the cusp of finding a cure for type 2 diabetes and obesity. To think, all the health issues that are cause in results of diabetes and obesity that could be cured from healthy bacteria. There would be no need for medication, just a prescription for natural healthy bacteria. Although, this study has not been conducted on humans, I believe the study is not far away. As a person who has tried to lose weight in the pass and discovered the older I get, the harder it becomes to keep the weight off, this is good news to my ears. It’s a dream come true to be able to think about, just drink a glass of water enhanced with natural bacteria to keep my weight off. The weight loss market is huge and if this is brought to market, it would put all the other companies out of business. There are harmful ingredients in weight loss supplements today that can cause harm to your body. I think most people would agree, if given a choice to take an unhealthy weight loss pill or to take bacteria, that occurs naturally in your body, I think everyone would chose the bacteria. Something so simple has been made complicated for years and now we might be on the edge of solving one of our biggest health issues. 

1 comment:

  1. Interesting study. Do they plan to continue with studies on humans?